Reclassifying a Thyroid Tumor
Led by researchers at the University of Pittsburgh School of Medicine, an international panel of pathologists and clinicians has reclassified a type of thyroid cancer to reflect that it is noninvasive and has a low risk of recurrence. The name change, described today in JAMA Oncology, is expected to reduce the psychological and medical consequences […]
Now Able To Image Up To 24 Specific BioMolecules
Researchers at Columbia University have made a significant step toward breaking the so-called “color barrier” of light microscopy for biological systems, allowing for much more comprehensive, system-wide labeling and imaging of a greater number of biomolecules in living cells and tissues than is currently attainable. The advancement has the potential for many future applications, including […]
Oncodomains and How They Affect Cancer-Causing Mutations
Scientists have identified thousands of previously ignored genetic mutations that, although rare, likely contribute to cancer growth. The findings, which could help pave the way to new treatments, are published in PLOS Computational Biology. Cancer arises when genetic mutations in a cell cause abnormal growth that leads to a tumor. Some cancer drugs exploit this […]
Bile Duct Cancer and Potential Risk Factor-Bacteria
An international research collaboration has identified bacteria in the bile duct as a potential risk factor in the development of bile duct cancer, or cholangiocarcinoma (CCA), a rare but aggressive form of cancer with symptoms that do not present themselves at the early stages. CCA is associated with multiple risk factors that are geographically distinct […]
Do Anxiety and Depression have An Effect On Lung Cancer Survival Rates?
Patients who experience anxiety and depression after being diagnosed with advanced lung cancer are more likely to die sooner, according to new research from the University of British Columbia and BC Cancer Agency. The study, published this month in the Journal of Pain and Symptom Management, is among the first to examine the effect of […]
How are EGFR (Epidermal Growth Factor Receptors) Connected To Cancer?
EGFR (Epidermal Growth Factor Receptors) are involved in the development and progression of many types of cancer and bowel cancer (colon carcinoma) in particular. So-called anti-EGFR antibodies are used in the treatment of bowel cancer patients, to inhibit EGFR. However, for reasons that are not yet clear, not all patients benefit from this treatment. This […]
An Anti-Malaria Drug Used In Cancer Treatment
After her brain cancer became resistant to chemotherapy and then to targeted treatments, 26-year-old Lisa Rosendahl’s doctors gave her only a few months to live. Now a paper published January 17 in the journal eLife describes a new drug combination that has stabilized Rosendahl’s disease and increased both the quantity and quality of her life: […]
Is Prostate Cancer and High Blood Cholesterol Connected?
Now a team led by researchers at the Duke Cancer Institute have identified a cellular process that cancer cells hijack to hoard cholesterol and fuel their growth. Identifying this process could inform the development of better ways to control cholesterol accumulation in tumors, potentially leading to improved survival for prostate cancer patients. The findings are […]
The Protein Complex That Protects Telomeres — The Ends Of Our Chromosomes
Scientists at The Wistar Institute have unveiled part of the protein complex that protects telomeres — the ends of our chromosomes. The study, published online in Nature Communications, explains how a group of genetic mutations associated with this protein complex contributes to various cancers. Telomeres are the protective structures at the end of chromosomes and […]
A nanoscale product of human cells plays an important role in intercellular communication
A nanoscale product of human cells that was once considered junk is now known to play an important role in intercellular communication and in many disease processes, including cancer metastasis. Researchers at Penn State have developed nanoprobes to rapidly isolate these rare markers, called extracellular vesicles (EVs), for potential development of precision cancer diagnoses and […]
