Georgetown Lombardi Comprehensive Cancer Center researchers have used animal models to reveal new information about the impact — positive and negative — that soy consumption could have on a common breast cancer treatment. The scientists have uncovered the biological pathways in rats by which longtime soy consumption improves effectiveness of tamoxifen and reduces breast cancer recurrence. But they also show why eating or drinking soy-based foods for the first time while being treated with tamoxifen can, conversely, reduce effectiveness of … Read More
The Link Between A High-Fat Diet And Breast Cancer
Feeding pregnant female mice a diet high in fat derived from common corn oil resulted in genetic changes that substantially increased breast cancer susceptibility in three generations of female offspring, reports a team of researchers led by scientists at Georgetown Lombardi Comprehensive Cancer Center. Their study, published online today in Breast Cancer Research, suggests a research direction for examining the diet of pregnant women, says the study’s senior author, Leena Hilakivi-Clarke, PhD, professor of oncology at Georgetown Lombardi. “It is … Read More
Breast Cancer Study Update
The study questions whether reliance on insufficiently-validated antibodies has led science down a dead-end path since the discovery of estrogen receptor beta (ESR2) in the 1990s. Cecilia Williams, a researcher at KTH Royal Institute of Technology in Stockholm and the joint research center, Science for Life Laboratory (SciLifeLab), says the beta receptor’s discovery changed our understanding of estrogen signaling. It also raised hopes for a new endocrine treatment to complement the success of estrogen-blocking drugs such as Tamoxifen. These therapies … Read More
Possible Link Between Hair Dyes and Breast Cancer Studied
The new study explores the link between popular hair products and breast cancer risks. In particular, chemicals in these products, including dyes and relaxers, have been implicated to be carcinogenic in some animal studies. However, the evidence for this link remains somewhat inconclusive. To better understand the link, researchers analyzed data from nearly 4,300 women with and without breast cancer. The researchers then teased apart other factors that could have influenced breast cancer risk, such as family medical history, alcohol … Read More
Study Suggests Unhealthy Food Choices Increase Breast Cancer Risk
French authorities are considering the implementation of a simplified nutrition labelling system on food products to help consumers make healthier food choices. One of the most documented candidates (Five-Color Nutrition Label/Nutri-score) is based on the British Food Standards Agency Nutrient Profiling System (FSA-NPS), a score calculated for each food/beverage using the 100 g amount of energy, sugar, saturated fatty acid, sodium, fibers, proteins, and fruits and vegetables. To assess its potential public health relevance, studies were conducted on the association … Read More
Breast Cancer Research – New Tests and Treatments
UC Davis graduate develops new breast cancer test A new test for invasive breast cancer has been developed by Angela Courtney, a recent Ph.D. graduate from the University of California, Davis. Courtney received her Ph.D. in integrative pathobiology from UC Davis in 2015, shortly after being diagnosed with breast cancer herself. Determined to find a test that would allow women to detect breast cancer earlier and without the risks and cost of mammograms, Courtney focused on leveraging the body’s natural … Read More